Medchemexpress/Ademetionine(Synonyms: S-Adenosyl-L-methionine; S-Adenosyl methionine; SAMe; AdoMet)/HY-B0617/100mg,MCE,,MCE,MedChemExp,MedChemExpress,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Medchemexpress/Ademetionine(Synonyms: S-Adenosyl-L-methionine; S-Adenosyl methionine; SAMe; AdoMet)/HY-B0617/100mg

产品编号：HY-B0617-50mg

市场价：¥1400.00

场地：美国(厂家直采)

产品分类：生化试剂>生物分子>小分子>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$70.00

品牌： MCE

公司：Medchemexpress

公司分类：

商品介绍

Ademetionine(S-adenosyl-l-methionine;SAMe)isanaturally-occurringsubstancewhichisamajorsourceofmethylgroupsinthebrain.

Description

Ademetionine(S-adenosyl-l-methionine;SAMe)isanaturally-occurringsubstancewhichisamajorsourceofmethylgroupsinthebrain.Target:OthersS-adenosyl-l-methionine(SAMe)isanaturally-occurringsubstancewhichisamajorsourceofmethylgroupsinthebrain.TheefficacyofSAMeintreatingdepressivesyndromesanddisordersissuperiorwiththatofplaceboandcomparabletothatofstandardtricyclicantidepressants.SinceSAMeisanaturallyoccurringcompoundwithrelativelyfewside-effects,itisapotentiallyimportanttreatmentfordepression[1].S-adenosylmethionine(SAMe)isadietarysupplementusedinthemanagementofosteoarthritis(OA)symptoms.StudiesevaluatingSAMeinthemanagementofOAhavebeenlimitedtoNonSteroidalAnti-inflammatoryDrugs(NSAIDs)forcomparison.ThepresentstudycomparestheeffectivenessofSAMetoacyclooxygenase-2(COX-2)inhibitor(celecoxib)forpaincontrol,functionalimprovementandtodecreasesideeffectsinpeoplewithosteoarthritisoftheknee[2].

ClinicalTrial

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References

[1].Bressa,G.M.,S-adenosyl-l-methionine(SAMe)asantidepressant:meta-analysisofclinicalstudies.ActaNeurolScandSuppl,1994.154:p.7-14.
[2].Najm,W.I.,etal.,S-adenosylmethionine(SAMe)versuscelecoxibforthetreatmentofosteoarthritissymptoms:adouble-blindcross-overtrial.[ISRCTN36233495].BMCMusculoskeletDisord,2004.5:p.6.

PreparingStockSolutions

ConcentrationVolumeMass	1mg	5mg	10mg

1mM	2.5098mL	12.5489mL	25.0979mL
5mM	0.5020mL	2.5098mL	5.0196mL
10mM	0.2510mL	1.2549mL	2.5098mL

Pleaserefertothesolubilityinformationtoselecttheappropriatesolvent.

References

[1].Bressa,G.M.,S-adenosyl-l-methionine(SAMe)asantidepressant:meta-analysisofclinicalstudies.ActaNeurolScandSuppl,1994.154:p.7-14.
[2].Najm,W.I.,etal.,S-adenosylmethionine(SAMe)versuscelecoxibforthetreatmentofosteoarthritissymptoms:adouble-blindcross-overtrial.[ISRCTN36233495].BMCMusculoskeletDisord,2004.5:p.6.

MolecularWeight

398.44

Formula

C₁₅H₂₂N₆O₅S

CASNo.

29908-03-0

Storage

Powder	-20°C	3years
	4°C	2years
Insolvent	-80°C	6months
	-20°C	1month

Shipping

RoomtemperatureincontinentalUS;mayvaryelsewhere

Solvent&Solubility

H₂O:≥43mg/mL;DMSO:≥100mg/mL(Needultrasonic)

*"<1 mg/ml"="" means="" slightly="" soluble="" or="" insoluble.="" "≥"="" means="" soluble,="" but="" saturation="">

Purity:>98.0%

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